genetic engineering

DMD2CURE · Correction of duplications in the DMD gene by a CRISPR/Cas9 approach

Wnt and CRC · Therapeutic inhibition of the oncogenic Wnt/beta-catenin pathway in mismatch repair deficient hypermutant tumors

ZF-ILC · Characterization of zebrafish innate lymphoid cells and IL-22

DrugCrops · Drought discovery to improve drought tolerance in crops

NGECA · REGULATION OF NEURONAL GENE EXPRESSION THROUGH CHROMOSOME ARCHITECTURE

BRCANCER · A novel approach for modeling development of breast cancer

2 partners · 2 countries

TransSplicHD · Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease.

AutoStopS · GluCl as an epileptic seizure autoregulatory Gene therapeutic approach

MYCO TRAPS · New roles for the cytoskeleton in cell-autonomous immunity to mycobacteria

NMDARETT · Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits

MRCKa in cancer · Targeting Cancer Cell Invasion and Metastasis by Inhibition of the Serine Kinase MRCKa

HeteroCancerInvasion · Effect of heterogeneity of cancer cells on collective invasion

BIO-Banana IN and OUT · BIO: Banana IN and OUT - engineering resistance against Panama disease in banana

GRNHairCell · Understanding the Gene Regulatory Network involved inner ear Hair Cell differentiation

HairGen · Genetics of human hair form diversity

HEAT-WHEAT · Highly Efficient and Thermotolerant Wheat

2 partners

RecInRep · Beyond double-strand break repair: specific mechanisms of homologous recombination at stressed replication forks.

SLIM · Synthetic Lethal Interactions with nucleophosMin 1

LIPID IMMUNITY · Regulation of lipid-mediated immunity in the intestine

EnterTerra · Transcriptional regulation and mechanistic insights on the telomeric lncRNA TERRA

PRIISM-HD · Pathways Regulating Intramyocellular Insulin Sensitivity and Metabolism in Health and Disease

2 partners · 2 countries

MIMIC · Mimicking organs on chips for high throughput drug screening and basic research

5 partners · 3 countries

germcells · A platform for the generation of human gametes in vitro

DUALgRENP · A DUAL gRNA system for functional assessment of ENhancers in Pluripotency