inflammatory bowel disease

Signalling-in-NODs · Investigation of the role and mechanism of action of NOD2-mediated isoform selective PI3K signalling in gut immunity and inflammation

MUC · The microbial degradation and utilization of mucin by Bacteroides in ulcerative colitis

2 partners · 2 countries

Glyco-Platforms · Novel smart glyco-nanomaterials as targeted therapeutics.

MArylAND · At the host-bacteria interface: Modulation of the intestinal microbiota and its metabolic activity by Card9 signalling in health and Inflammatory Bowel Diseases

ColoFILM · Multifunctional polymeric film-based drug delivery system for oral anti-TNF-alpha-based inflammatory bowel disease therapy

MIRA · Characterizing Microbe-specific Immune Responses in the pathogenesis of Autoimmunity

EvolVir · Evolution of virulence in immune-compromised hosts and the adaptation of emerging viruses

ZF-ILC · Characterization of zebrafish innate lymphoid cells and IL-22

OBESOGENS · Environmental chemicals as obesogens

2 partners · 2 countries

Gut-InflammAge · Age-associated signatures in the composition and pro-inflammatory status of the gut microbiome in humans and mice, and the impact of a periodic fasting intervention to promote healthy aging

MAIT · Evolutionary conserved T cells specific for a microbial metabolite: deciphering their development in the thymus and mapping their interactions with the gut microbiota in vivo.

SLIM · Synthetic Lethal Interactions with nucleophosMin 1

LIPID IMMUNITY · Regulation of lipid-mediated immunity in the intestine

fetISC · Characterizing drivers of intestinal tissue maturation in vitro and in vivo

KCs and Gut Antigens · Elucidating the role of liver resident Kupffer cells in the regulation of the immune responses to intestinal antigens

Tbet ILC JFN · The role of innate lymphoid cells in regulating intestinal inflammation

IPEIBD · Identification of promoters and enhancers specific for inflammatory bowel disease and its subtypes

WORMTUMORS · Worm power: Can helminths modify the development of colorectal cancer?

2 partners · 2 countries

GUTWORM · Unravelling host intestine-parasite interactions that define immune responses to whipworms

IMSTREV · Immune modulation by lymph node stromal cell-derived extracellular vesicles

GutILC3 · Cell-cell interactions critical to ILC3 function in the human gut

OTULINVIVO · The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo

EPIMAC · The next generation epigenetic medicine for inflammation

5 partners · 3 countries

EPIREP · Characterization of epithelial wound repair at the molecular level for revealing epithelial aspects of inflammatory bowel disease