oncology

RegARcis · Role of the SWI/SNF complex in the Androgen Receptor cistrome regulation

Irrev Fork Arrest · Deciphering the mechanism of irreversible replication fork arrest

CATKERB · Total Syntheses of Catharanthine and Keramaphidin B by an Iridium-Catalyzed Reductive Cyclization Cascade

RMAG · Rheology and Mechanics of Active Glasses

ChRONAM-H · Chromatin Regulation Of Normal And Malignant Haematopoiesis

SPOT · Synthesis of Pretargeted Oncology Theranostics

MAMBO · Magnetic swArms for liver chemoeMBOlization

2 partners · 2 countries

TGF-BTB · Transforming Growth Factor – Bench To Bedside. Towards a better understanding of TGF-β isoform specific signalling in health and disease

2 partners · 2 countries

BESG · Bioengineered exosomes based approaches for the effective treatment of non-small cell lung cancer

HollidayTrack · Tracking the movement and dynamics of Holliday junctions

StressRhomboid · Trapping intramembrane protease substrates in living cells: focus on RHBDL4 role in ERAD

NetriCan · Characterization of the role of netrin-1 in the regulation of the Epithelial-to-Mesenchymal Transition during tumor progression.

cONCReTE · DevelOpmeNt of Cancer RNA TherapEutics

17 partners · 7 countries

GrowthDevStability · Characterization of the developmental mechanisms ensuring a robust symmetrical growth in the bilateral model organism Drosophila melanogaster

FBC predisposition · Unraveling novel Familial Breast Cancer (FBC) predisposition genes.

METABONE · A new approach of metastatic bone fracture prediction using a patient-specific model including metastatic tissue, daily-life activities and local failure criteria

BraINstorm · Engineered nanocarriers for simultaneous anticancer immune response and “switching” of tumor-associated macrophages for intranasal glioblastoma treatment

BRCAstem · Monitoring cancer stem cell dynamics and therapeutic response in BRCA2-deficient breast tumour cells

SynWaiXen · Total Synthesis of Waixenicin A and Xenibellol A

LINKER · Elucidating transcriptional rewiring on hematological malignancies via computational methods

TESTIMONY · Tumor Endothelial Cells: Gatekeepers Of Anti-Tumor Immunity

MelImmuneOrg · Deciphering the tumor-immune-microenvironment profile and organization within the tumors of melanoma patients undergoing immunotherapy

ClickandTreatCancer · Ligand Directed NIR-based Theranostic Prodrugs for Prostate Cancer

RECOBIN-PROTACs · Reversible Covalently Binding PROTACs Technology for Protein Degradation in Cancer Therapy