clinical medicine

mTORmorS · Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma

METHYVIREVOL · Virocellular hybrids and epigenomic changes as driving factors of infection driven cancers.

M-Lysosomes · Identification of a novel function of lysosomes in mitosis for cancer therapy

PROMPT · New generation of porphyrinoids for mitochondria-targeted photodynamic therapy

MAGNET-CELLPATCH · Multimodal magnetic cellular-patches with synergistic effects for high performance theranostics

EpiBigDatainWomen · Epigenetic Data Integrated in a Big Data Approach to Unravel Novel Pathzays of CV Risk independent of classical CVD Risk Factors in Women.

UNNAMEd-2 · Unraveling the conceptional novel ADAM17 regulation by PP2A in metastasis formation.

ProLung · The role of maternal microbiota in offspring lung development and function

TUNING-BRAKES · Fine-tuning the brain’s brakes – modulating inhibitory control with transcranial alternating current stimulation

YAP MECHANO · Elucidating the mechanism of mechanotransduction through YAP and TAZ

MECHANOSITY · Mechanical regulation of cellular behaviour in 3D viscoelastic materials

2 partners · 2 countries

COLOVOC · Reliable and specific urinary biomarkers for colorectal cancer

2 partners · 2 countries

ProCenDecl · Synthesis and validation of chemical Probes for Centrosome Declustering: development of potent and selective anti-cancer agents.

PNECtumor · Mechanisms regulating pulmonary neuroendocrine cell (PNEC) growth and tumorigenesis

MECHANOIDS · Probing and controlling the three-dimensional organoid mechanobiology

NEMoCuRe · Role of S-Nitrosylation of epigenetic modifiers in vascular regeneration

OPTOLEADER · Optogenetic control of leader cell mechanobiology during collective cell migration

INMARE · Injectable hydrogels for magnetically-activated, remote-controlled drug delivery

2 partners · 2 countries

LEUKEYOLK · Uncovering the origin and mechanisms of Down syndrome-associated leukaemia through human induced pluripotent stem cell-derived haemopoiesis

rDNAstress · Novel insights into DNA damage and stress responses in the nucleolus: Mechanisms and relevance for genomic (in)stability and cancer

Gal3-BrainMets · A novel immunotherapy against brain metastasis: Anti-Galectin-3

PREMOTHER · PREvention of MOther-to-child Transmission of HIV and Syphilis using an Electrochemical Readout based on DNA Switches

ONCOTHERANOSTICS · Advanced Theranostic Nanomedicines for Oncology. Development of new combinatorial therapies for primary and metastatic Breast Cancer.

2 partners · 2 countries

O6-alkylguanines · Characterisation and quantification of O6-alkylguanine DNA adducts derived from nitrosated amino acids: Risk factors in colorectal cancer.