cell biology

SCHENGEN-ROOT · 'Filling the gaps' in the Schengen pathway for plant root Casparian strip integrity

UNPACK PD-L1 · Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells

mRNAstress · Investigating the molecular mechanisms of translational reprogramming during cellular stress

RESISTREE · Identification of Phytophthora resistant beech trees by composition of endophyte communities, lesion formation and phenomics approaches.

signalling dynamics · Bridging biophysics and cell biology: The role of G protein-coupled receptor conformations in signalling

2 partners · 2 countries

EUREKA · Design of multifunctional phosphorous dendritic systems for drug delivery

LYSOKIN · Architecture and regulation of PI3KC2β lipid kinase complex for nutrient signaling at the lysosome

EmbryoPAINT · PAINTing the architecture of the totipotency gene network during early mammalian development

CheckBacZ · Checkpoints in the bacterial cell cycle: role of the cytokinetic Z-ring and implications for antibiotic resistance

uTSSreg · Regulation of mammalian genes by new classes of promoter proximal transcription start sites

IMaP · Imaging tumor vessels as a marker for p53 mutation status in cancer

OCTOBER · Control of cell identity in pluripotent and germline cells by OCT4 orchestration of chromatin binding and enhancer regulation

proEVLifeCycle · The life cycle of extracellular vesicles in prostate cancer: from biogenesis and homing, to functional relevance

10 partners · 6 countries

SECRET · Exploitation of the SECRETory pathway for cancer therapy to address European research

12 partners · 8 countries

MMM-REBIO · Mixotrophy in marine microalgae for renewable biomass production

THIAZOLIUMenzyme · Enzyme design and engineering by implementation of non-canonical amino acids in protein scaffolds

PI3K-in-tolerance · PI3K delta role in dendritic cell antigen processing and presentation to control gut tolerance

Clock-SAM · Transcriptional reprogramming of Clock at Shoot Apical Meristem in regulating plant organogenesis and growth.

PhotoXLink · Development of biomolecular tools for the spatiotemporal photocontrol of AMPA receptors mobility

ADAPT2FLOW · Adaptive and maladaptive endothelial cell dynamics during blood flow-driven vascular patterning

SUMO-PCDH10 · Physiological consequences of Protocadherin-10 sumoylation on neuronal function.

GERMINOID · Development of human primordial germ cells towards the onset of sperm and egg differentiation in a novel model culture system

DEAP · Development of Epithelium Apical Polarity: Does the mechanical cell-cell adhesions play a role?

PulsatERK · Intracellular ERK signalling dynamics mediated epidermal stem cell fate control