biomolecules

FLYMEN · A Drosophila model for understanding the basis of Meniere’s disease

evoDISFOLD · Decoding Coupled Folding and Binding via Single-Molecule characterization of Ancient IDP protein-protein Interactions

WolAntiS · Using antisense inhibition to understand Wolbachia symbiosis and antiviral protection

Upbiosens · Near-infrared nucleic acids sensing and imaging using lanthanide-based nanoparticles capped with DNA

FA x Force · Reconstitution and Structural Analysis of a Minimal Mechanosensitive Focal Adhesion Complex

RNAmpMax · Maximization of amplification of next-generation RNA replicon vaccines through synergistic molecular and formulation design

SHINE · Self-Healthcare for breast cancer detection using an INtegrated paper-based Electrochemical device

HIV VCC Interference · Characterisation of single molecule dynamics within HIV-1 reservoirs as a target for interference with virus persistence and immune evasion

Meta-Origami · Metabolic engineering of Ustilago trichophora: an isotope-assisted metabolomics approach for the improvement of malate production from glycerol

MHCIbiopic · MHC-I biogenesis and degradation at the endoplasmic reticulum membrane

Stress Granules · Using Reconstituted Stress Granules to Gain Insight into the Molecular Pathology of Neurodegenerative Diseases

TCELLTIGIT · Structural characterization of immune signaling protein TIGIT using x-ray crystallography and cryo-electron microscopy

MechDeath · Study of the mechanical cues driving cell competition and its role in pretumoral cell expansion

DEVINAC · Identifying the proteins of the cochlear mechanoelectrical transduction machinery that are also involved in the development of auditory cortex interneurons.

CL_Exocytosis · “Molecular dissection of cytotoxic lymphocyte exocytosis

ChemRAS · Chemical probing of transcriptional RAS effectors

NovoFold · De novo protein discovery as a tool for understanding the folding conundrum

EFHHBBBMS · Endothelial Hedgehog autocrine signaling at the Blood Brain Barrier controls inflammatory Central Nervous System lesion size and severity through Gas1 co-receptor modulation.

BiT-XLMS · Development of comprehensive and user-friendly bioinformatics tools to study protein structures and interactions in mass spectrometry-based chemical cross-linking

Alpha-Synuclein · Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors.

PoLiMeR · Polymers in the Liver: Metabolism and Regulation

19 partners · 8 countries

INTEGRATA · Integrating chemical and biological approaches to target NAD production and signaling in cancer

15 partners · 6 countries

synBIOcarb · Synthetic biology of carbohydrate-binding proteins: engineering protein-carbohydrate interactions for diagnostics and cell targeting

15 partners · 8 countries

UCOM · Ultrasound Cavitation in Soft Materials

17 partners · 8 countries