mutation

MOBODS · Multi-Omics Brain Organoid dissection of Dravet Syndrome

CARABELA-NF1 · CDK4/6i Resistance and Biomarker Analysis in Neoadjuvant settings from CARABELA trial.

LEGEND · LysoIP based-lysosomal signatures in Parkinson's Disease

2 partners · 2 countries

FluZoBa · Elucidating the molecular mechanism by which BTN3A3 mediates host restriction against zoonotic influenza virus infection.

SLC-Mn-HMNDYT2 · Identifying and exploiting SLC39A14 regulatory mechanisms for the future development of therapeutics

RAFAEL · Using synthetic lethality to identify functional genetic Relationships in microAlgae: The next step For systemAtic gEnetic interactions anaLysis in Chlamydomonas reinhardtii

TOR-TREKking · Inhibition of the potassium channel TREK1 by mTOR: a mechanism for aberrant neuronal excitability in mTORopathies

DeepScalePPIs · Massively scaling-up protein-protein interaction mutagenesis.

EpiDM · Uncovering the role of the m6A epitranscriptome in Myotonic Dystrophy Type 1 (DM1)

2 partners

IMMUNOPREVENT · Leveraging the immune system for breast cancer prevention

STRIM-HCC · Defining the role of stromal cells in determining HCC patient response to immunotherapies at single-cell resolution

EpiGlyco · Mechanistic insight into the role of glycosylation in focal cortical epilepsy through modelling in brain organoids.

TUNENALCN · Regulation and modulation of the NALCN channelosome

CAFinCAC · Dissecting and targeting malignant cell-fibroblast crosstalk driving cachexia in pancreatic cancer

SYNGAP-IsoDev · The role of SYNGAP1 isoforms in brain development

3 partners · 2 countries

Epi-BCE · Epigenetics of Bladder Cancer Evolution.

2 partners · 2 countries

CrisEU · Reinvented through Crises: The Political Economy of the Western European Left within European Integration

2 partners · 2 countries

RETRO · Relapse in T-ALL: Resistant Clones and Therapeutical Options

2 partners

SPADYN-SM · Spatiotemporal dynamics of secondary metabolism in the ocean microbiome

2 partners · 2 countries

Novel GIST Therapies · Targeted Protein Degradation as a Therapeutic Strategy for the Treatment of Gastrointestinal Stromal Tumour (GIST)

RhythMEC · Arrhythmogenesis in Dilated Cardiomyopathy: Role of Mechano-Electric Coupling

3 partners · 2 countries

DELLAsFixGenome · Regulation of the DNA Repair Response by DELLA proteins

LAMA2-TFIMG · Tackling fibrosis and inflammation in LAMA2-RD by in vivo modulation of a novel modifier gene

EpiMetaPDO · Dissecting mechanisms of epigenetic reprogramming driving metastatic transition using cancer patient-derived organoids