mutation

MindTheGAP · Correction of SynGAP haplodeficiency-related defects in AMPA receptor dynamic nanoscale organization

2 partners

PRERES · Predicting protein evolutionary trajectories toward resistance against antiretroviral treatments

noCOLDmore · Reprogramming eNdOthelial cells in immune-COLD tuMORs

2 partners · 2 countries

VIVACE · Management of avian influenza in a vaccination context

21 partners · 8 countries

EVO-PDAC · Evolutionary dynamics of pancreatic cancer at single-cell and spatial levels

NEUROINFLAM-MS · Proteomics of neuroinflammatory signaling: Illuminating cellular mechanisms driving neurodegenerative diseases

CrowdControl · Identifying the mechanism underlying intracellular density homeostasis.

2 partners · 2 countries

IMMSYM · Mechanistic insight into immune control of cnidarian endosymbiosis

CYNAMIS · Clonal dynamics and mitochondrial dysfunction in hematopoiesis following chemotherapy

DETECT-SV-RD · Decoding hidden Structural Variants in unsolved Rare Genomic Diseases

TARAF · Taxonomy and azole resistance in Aspergillus section Flavi

ProgeroidNPC · Mechanistic understanding towards how progerin contributes to premature ageing

CPRrescue · Identifying ChloroPlast Ribosome rescue mechanisms under genetically induced and environmental stresses

PancmiR · Biomimetic collagen-based scaffolds for the study of pancreatic cancer and delivery anti-tumoural miRNA for enhanced cancer therapy.

MIND-NHE6 · Molecular Insights into human NHE6: From Dimerization to Disease Implications

CF.Nbs.PA-SA · Development of Nanobodies against Pseudomona aeruginosa and Staphylococcus aureus and evaluation as immunotherapeutics

BRAINMOS · Brain Mosaicism Matters: Organoids in focus to unveil mechanisms in epileptogenic cortical malformations

HeartRepairKIT · Structural, kinetic, and biophysical analysis and engineering of KIT.METRNL signalling to boost heart tissue regeneration after myocardial infarction

2 partners · 2 countries

CRISPRGels · Rational Nanoparticle Design for Efficient Transmucosal CRISPR Delivery in Cystic Fibrosis – “CRISPRGels”

5 partners · 3 countries

IMMERGE · Storming Immune Monogenic Conditions through Multiomic and Gene Editing Approaches

27 partners · 8 countries

NIR-NanoCAR · Near-Infrared Photothermal Nano-CAR Immunotherapy mediated by engineered exosomes targeted to pancreatic cancer with mutated KRAS

2 partners · 2 countries

Psy-hiPSC microglia · Functional impact of the psychiatric risk gene CACNA1C in human iPSC-derived microglia

PervasiveTranscript · Controlling Pervasive Transcription

ExploNL1 · Exploring the role of Neuroligin-1 in synapse formation and function

2 partners