gene therapy

ACtIVAtE · The virulence potential of human pathogens: how Acinetobacter baumannii survives Acanthamoeba castellanii predation

GREEN-SPECIALISTS · Specialised plant cell types via developmentally-controlled gene knockouts: a key step towards fully customised plants

REACT · Uncovering the role of cis genetic elements in antigenic variation of Plasmodium falciparum using the CRISPR-Cas9 genome editing technology

FIMBUG · Heterogeneity in fimbrial length and abundance as a generic regulator of E. coli surface colonization

ORI NUMBER · Unravelling the effect of origin number on the success of genome replication

IMGENE · Improving Genome Editing Efficiency (IMGENE)

10 партньори · 8 държави

EvoCellFate · Evolution of cell fate decision during development

BaskAtax · Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders

BCRdangerCOMPETITION · The role of danger signal and cellular competition in the elimination of B cells lacking the B cell receptor.

StressEBOV · Ebola virus manipulation of the cellular stress responses

ARTENGINE · Artificial Life Today Anthropological and Sociological Analysis of Life Engineering

MetEpiClock · Circadian Control of Histone Methylation Dynamics through the Fine-tuning of Methionine Metabolic Flux

2 партньори · 2 държави

rDNAevol · Population genomics and experimental evolution of ribosomal RNA gene variants in Arabidopsis thaliana

Repro_organoid · Direct reprogramming of human astrocytes into functional neurons in cerebral organoids derived from genome edited hiPSCs

RhoSNATCH · Dissecting Rho GTPase signalling networks through acute perturbation techniques

GlycoModels · 3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management

3D NEONET · Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics

22 партньори · 7 държави

circRTrain · circular RNA Biology Training Network: from biogenesis to biomarkers

12 партньори · 6 държави

MMBio · Molecular Tools for Nucleic Acid Manipulation for Biological Intervention

19 партньори · 7 държави

DMD2CURE · Correction of duplications in the DMD gene by a CRISPR/Cas9 approach

Wnt and CRC · Therapeutic inhibition of the oncogenic Wnt/beta-catenin pathway in mismatch repair deficient hypermutant tumors

ZF-ILC · Characterization of zebrafish innate lymphoid cells and IL-22

NGECA · REGULATION OF NEURONAL GENE EXPRESSION THROUGH CHROMOSOME ARCHITECTURE

BRCANCER · A novel approach for modeling development of breast cancer

2 партньори · 2 държави