mutation

ORI NUMBER · Unravelling the effect of origin number on the success of genome replication

IMGENE · Improving Genome Editing Efficiency (IMGENE)

10 партньори · 8 държави

TreasureDrop · Directed Evolution of Enzyme for Applied Biocatalysis at Ultrahigh Throughput in Picoliter Droplets

CFZEBRA · Balancing the immune response in cystic fibrosis: using zebrafish models of infection and inflammation to uncover new therapeutic approaches

BaskAtax · Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders

HEGEMONIC · HEpatocellular carcinoma GErmline MutatiONs ImpaCt (HEGEMONIC)

CHIROGLU · Comparative genomics of sugar-eating bats: Implications for the genetics of glucose metabolism and diabetes

HOST-SELECT · Functional Analysis of Host Genetic Variants: Biomarker Selection Towards Improving Female Subfertility Diagnosis and Treatment

Pharynx2016 · Evolution and development of pharyngeal pouches and pre-oral gut in basal fishes

IDRAM · The role of amphidial drug uptake in the mode of action and resistance to ivermectin in nematodes of livestock

SAS6-Cep135-CPAP · Towards a molecular understanding of the centriole assembly process

MuSCel Genome · Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization

MSCFate · Fate of mammary stem cells during tumorigenesis and clinical implications

ENDOCAM · TARGETING ENDOTHELIAL CELL AND CANCER AMOEBOID MOVEMENT TO OVERCOME RESISTANCE TO ANTI-VEGF AND ANTI-PROTEASE THERAPIES

2 партньори · 2 държави

rDNAevol · Population genomics and experimental evolution of ribosomal RNA gene variants in Arabidopsis thaliana

Epi-Somaclone · Epigenetically Stable Cloned Plants: Increasing The Epigenetic and Phenotypic Diversity of Plants through Tissue-Specific Regeneration

ReXeG · Deciphering molecular mechanisms that resolve mutagenic DNA G-quadruplex structures

SpliceCore · Functional dissection of core spliceosomal mutations causing Retinitis Pigmentosa.

MuRChap · The mutation-buffering capacity of RNA chaperones

EnzVolNet · COMPUTATIONAL EVOLUTION OF ENZYME VARIANTS THROUGH CONFORMATIONAL NETWORKS

GlycoModels · 3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management

DSR · Dissipative Self-Replication

ChroSoDSB · Chromatin Study of DNA Double Strand Breaks

MDRZYMES · Multidrug resistance gene regulators as scaffolds for the design and evolution of artificial metalloenzymes